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Question 1 of 10
A 35-year-old patient has been prescribed sodium bicarbonate capsules for the correction of metabolic acidosis. She is to take ten capsules in a day. Each capsule contains 500 mg of sodium bicarbonate.
The molecular mass of sodium bicarbonate (NaHCO3) is 84.
How many millimoles each of sodium (Na+) and bicarbonate (HCO3-) would this patient take in a day? Give your answer to one decimal place.Correct
Question 2 of 10
Mrs A presents a prescription for prednisolone 5 mg enteric-coated (e/c) tablets.
What is the total quantity of prednisolone 5 mg e/c tablets that Mrs A would require for the full course of medication prescribed?Correct
Question 3 of 10
You have been asked to prepare 180g of a 1 in 5 dilution of betamethasone valerate 0.1% ointment using emulsifying ointment as the diluent.
How many grams of emulsifying ointment is required to prepare the requested ointment?Correct
Question 4 of 10
Mr B is a 70 kg gentleman with atrial fibrillation. He requires an oral loading dose of digoxin to achieve a plasma digoxin concentration of 1.5 mcg/L.
Volume of distribution = 6 L/kg
Salt factor = 1
Bioavailability = 0.7
What is the oral loading dose of digoxin that Mr B requires?Correct
Question 5 of 10
Mrs C is terminally ill, and has been stabilised on Oramorph concentrated oral solution (morphine sulphate 100 mg/5 mL), 3 mL four times a day. As her pain is under control, her doctor decides to transfer her onto Durogesic DTrans (fentanyl) patches.
What strength of Durogesic DTrans patch should be prescribed for use every 72-hours to provide an equivalent analgesic effect to Mrs C’s normal dose of Oramorph concentrated oral solution?Correct
Question 6 of 10
A 7-year-old child who weighs 24 kg is suffering from community-acquired pneumonia and requires amoxicillin treatment by intravenous injection. The paediatrician prescribes a dose of 30 mg/kg every eight hours. The nurse reconstitutes a 1 g vial of amoxicillin sodium for injection with Water for Injections according to the instructions in the summary of product characteristics.
How many mL of the reconstituted injection solution should the nurse administer to this child per dose?Correct
Question 7 of 10
You are required to extemporaneously prepare 500 g of an ointment containing 35% Liquid Paraffin. You have an ointment that contains 55% Liquid Paraffin and another ointment which contains 15% of Liquid Paraffin.
What quantity expressed in grams of the 55% Liquid Paraffin ointment will you need to mix together with the 15% Liquid Paraffin ointment to make 500 g of the 35% Liquid Paraffin ointment?Correct
Question 8 of 10
Miss D is on remission from leukaemia and has been prescribed oral methotrexate at a maintenance dose of 25 mg/m2 twice weekly. Upon checking her medical notes you find that she is 0.9 m tall and weighs 12 kg.
Body surface area can be calculated using this formula:
What is Miss D’s weekly dose of methotrexate? Give your answer to one decimal place.Correct
Question 9 of 10
You are asked to prepare 50 mL of a solution of potassium permanganate of such strength that when diluted 20 times with water, a 1 in 10,000 solution is produced.
What is the quantity of potassium permanganate you would require to prepare the solution?Correct
Question 10 of 10
Mr E has been prescribed aminophylline 0.5 mg/kg/hour as a maintenance dose for a severe acute exacerbation of COPD to be administered via continuous intravenous infusion. 500 mg of aminophylline has been added to 500 mL glucose 5%. Mr E weighs 100 kg.
What rate in mL/hour should the infusion be run at?Correct