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Question 1 of 10
A 35-year-old patient has been prescribed sodium bicarbonate capsules for the correction of metabolic acidosis. She is to take ten capsules in a day. Each capsule contains 500 mg of sodium bicarbonate.
The molecular mass of sodium bicarbonate (NaHCO3) is 84.
How many millimoles each of sodium (Na+) and bicarbonate (HCO3-) would this patient take in a day? Give your answer to one decimal place.Correct
Question 2 of 10
Mrs A presents a prescription for prednisolone 5 mg enteric-coated (e/c) tablets.
What is the total quantity of prednisolone 5 mg e/c tablets that Mrs A would require for the full course of medication prescribed?Correct
Question 3 of 10
You have been asked to prepare 180g of a 1 in 5 dilution of betamethasone valerate 0.1% ointment using emulsifying ointment as the diluent.
How many grams of emulsifying ointment is required to prepare the requested ointment?Correct
Question 4 of 10
Miss C is to be switched from ferrous sulphate 200 mg tablets (taken three times daily) to ferrous gluconate tablets for her iron deficiency anaemia. Her doctor informs Miss C that she will be receiving an equivalent amount of iron per day as before, to the nearest tablet.
What is the total number of ferrous gluconate tablets Miss C would take in a day?Correct
Question 5 of 10
Mr E is a 68 year old man in hospital for a genital tract infection. He has renal impairment, with a creatinine clearance of 42 mL/min/1.73 m². The consultant has initiated treatment with ciprofloxacin IV 200mg IV q 12 hours as Mr E cannot currently take medication by mouth. It will be infused in a 100mL bag.
How many mLs per minute should be administered to Mr E? Give your answer to one decimal place.Correct
Question 6 of 10
Mr E is a 55-year-old man suffering from epilepsy for which he takes phenytoin 100 mg capsules, 200 mg twice daily. Mr E is now unable to swallow solid formulations. As a substitute, his doctor has requested for phenytoin oral suspension to be supplied (equivalent to his previous daily dose) twice daily for 28 days.
What is the total quantity in mL of phenytoin oral suspension that Mr E will require for the 28-day period? Give your answer to the nearest whole number.Correct
Question 7 of 10
You receive the following prescription for potassium permanganate solution.
Potassium permanganate, a sufficient quantity
Purified water, add to 400mL
5mL diluted to 1 litre to give a 1:8000 solution for use by patient
What is the total number of 200 mg potassium permanganate tablets you will require to compound this prescription?Correct
Question 8 of 10
Mrs A is 70 years old and has congestive heart failure. She weighs 50 kg, her last measured serum creatinine level was 170 micromol/L and the target serum digoxin concentration is 1.5 mcg/L.
Bioavailability (F) = 0.77 for digoxin elixir
Salt fraction (S) = 1
The formula for calculating creatinine clearance (mL/min) is provided below.
= constant x (140 – age in years) x weight (kg)/serum creatinine (micromol/L)
Constant is 1.04 for women and 1.23 for men
The formula for calculating digoxin clearance (mL/min) in patients with congestive heart failure is provided below.
= (0.33 x weight in kg) + (0.9 x creatinine clearance in mL/min)
The formula for calculating digoxin maintenance dose (mcg) is provided below.
= digoxin clearance (L/hour) x target concentration (mcg/L) x dosing interval (hour)/F X S
How many mL of digoxin elixir 50 mcg/mL would you recommend as a maintenance dose given every 24 hours for Mrs A? Give your answer to the nearest whole number.Correct
Question 9 of 10
A patient is prescribed temazepam oral solution (10 mg/5 mL) for a dose reduction regime as follows:
Week 1: 9 mg nocte
Week 2: 8 mg nocte
Week 3: 7.5 mg nocte
How many mL of temazepam oral solution is needed to provide the 3 week course of treatment for this patient? Give you answer to 1 decimal place.Correct
Question 10 of 10
Mr E has been prescribed aminophylline 0.5 mg/kg/hour as a maintenance dose for a severe acute exacerbation of COPD to be administered via continuous intravenous infusion. 500 mg of aminophylline has been added to 500 mL glucose 5%. Mr E weighs 100 kg.
What rate in mL/hour should the infusion be run at?Correct